Cardiopulmonary, Sedative, and Drug Disposition Effects of Vatinoxan in Sheep Receiving Dexmedetomidine, Medetomidine, Ketamine and Atipamezole
The impact of the peripherally selective α2-adrenoceptor antagonist, vatinoxan, on selected pharmacodynamic and pharmacokinetic properties of two selective α2-adrenoceptor agonists, medetomidine and dexmedetomidine, were investigated in sheep. Moreover, certain interactions between vatinoxan and atipamezole, a specific α2-adrenoceptor antagonist, were evaluated. The initial objective of ...
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